Current Scheduling Status
Year(s) and type of review / ECDD meetings
Drug Class

Recommendation (from TRS)

Substance identification
Chemical name: a-cyclohexyl-a-phenyl-1-piperidinepropanol.

WHO review history
Trihexyphenidy] has not been reviewed by the Expert Committee.

Trihexyphenidyl is an anticholinergic agent used in the treatment of parkinsonism and the extrapyramidal side-effects of neuroleptics. In animal tests, it is not reinforcing. In humans, it has hallucinogenic effects. Although there are a number of reports of abuse of trihexyphenidyl, the tendency for the abuser to repeat its use is limited because of its unpleasant anticholinergic effects. The Committee does not recommend trihexyphenidyl for critical review at this time.

ECDD Recommendation

No change in scheduling