Current Scheduling Status
None
Year(s) and type of review / ECDD meetings
Drug Class
Recommendation (from TRS)
Substance identification
Chemical name: a-cyclohexyl-a-phenyl-1-piperidinepropanol.
WHO review history
Trihexyphenidy] has not been reviewed by the Expert Committee.
Recommendation
Trihexyphenidyl is an anticholinergic agent used in the treatment of parkinsonism and the extrapyramidal side-effects of neuroleptics. In animal tests, it is not reinforcing. In humans, it has hallucinogenic effects. Although there are a number of reports of abuse of trihexyphenidyl, the tendency for the abuser to repeat its use is limited because of its unpleasant anticholinergic effects. The Committee does not recommend trihexyphenidyl for critical review at this time.
Chemical name: a-cyclohexyl-a-phenyl-1-piperidinepropanol.
WHO review history
Trihexyphenidy] has not been reviewed by the Expert Committee.
Recommendation
Trihexyphenidyl is an anticholinergic agent used in the treatment of parkinsonism and the extrapyramidal side-effects of neuroleptics. In animal tests, it is not reinforcing. In humans, it has hallucinogenic effects. Although there are a number of reports of abuse of trihexyphenidyl, the tendency for the abuser to repeat its use is limited because of its unpleasant anticholinergic effects. The Committee does not recommend trihexyphenidyl for critical review at this time.
ECDD Recommendation
No change in scheduling
Link to full TRS
who_trs_856.pdf1.07 MB