Current Scheduling Status
None
Year(s) and type of review / ECDD meetings
Drug Class
Recommendation (from TRS)
ECDD Technical summary
Furfenorex is the racemic N-furfuryl — analogue of methamphetamine. The drug is a sympathomimetic amine with anorectic activity. No toxicological data and few pharmacological data are available on the substance. It is possible that furfenorex is metabolized to methamphetamine in man. No data are available concerning the dependence potential in animals or man, and the nature and magnitude of the public health or social problems associated with its use or abuse are unknown. Since 1970, there have been reports from France of varying degrees of abuse. Brazil is the only country in which the substance is controlled. It has been used therapeutically as an anorectic, but no data are available on its efficacy. There is little evidence of illicit trafficking in furfenorex. In summary, there is no evidence, except for its structure and the possibility that it could be metabolized to methamphetamine, that
furfenorex has a pharmacological profile or dependence potential . similar to compounds already controlled under the Convention on Psychotropic Substances. Thus, the Expert Committee did not consider itself to be in a position to make any recommendation until more information about the compound becomes available. In addition, since no significant public health problems have been reported to be associated with the use or abuse of furfenorex, no recommendation for urgent control seemed to be necessary.
Furfenorex is the racemic N-furfuryl — analogue of methamphetamine. The drug is a sympathomimetic amine with anorectic activity. No toxicological data and few pharmacological data are available on the substance. It is possible that furfenorex is metabolized to methamphetamine in man. No data are available concerning the dependence potential in animals or man, and the nature and magnitude of the public health or social problems associated with its use or abuse are unknown. Since 1970, there have been reports from France of varying degrees of abuse. Brazil is the only country in which the substance is controlled. It has been used therapeutically as an anorectic, but no data are available on its efficacy. There is little evidence of illicit trafficking in furfenorex. In summary, there is no evidence, except for its structure and the possibility that it could be metabolized to methamphetamine, that
furfenorex has a pharmacological profile or dependence potential . similar to compounds already controlled under the Convention on Psychotropic Substances. Thus, the Expert Committee did not consider itself to be in a position to make any recommendation until more information about the compound becomes available. In addition, since no significant public health problems have been reported to be associated with the use or abuse of furfenorex, no recommendation for urgent control seemed to be necessary.
ECDD Recommendation
Scheduling/control not currently recommended
Link to full TRS
who_trs_729.pdf1.29 MB