Current Scheduling Status
Year(s) and type of review / ECDD meetings
Drug Class
Recommendation (from TRS)
ECDD Technical summary
Fenproporex is the racemic N-cyanoethyl analogue of amphetamine. Pharmacologically, the compound appears to be amphetamine-like, but few published data are available. No animal
toxicology studies are available; but, when given at therapeutic doses, the drug has been reported to alter colour vision in man. Fenproporex has been reported to be metabolized to amphetamine in man. No data are available concerning the preclinical or clinical dependence potential of the drug. There are a few reports of abuse from Chile and Mexico and the drug is controlled in several countries. Fenproporex is used therapeutically as an appetite suppressant and is marketed widely. There are a number of reports of illicit trafficking in the drug.
On the basis of the data outlined above, it was the consensus of the Expert Committee that fenproporex met the criteria of article 2, paragraph 4, for control under the Convention on Psychotropic Substances and should be placed in Schedule IV of the Convention.
Fenproporex is the racemic N-cyanoethyl analogue of amphetamine. Pharmacologically, the compound appears to be amphetamine-like, but few published data are available. No animal
toxicology studies are available; but, when given at therapeutic doses, the drug has been reported to alter colour vision in man. Fenproporex has been reported to be metabolized to amphetamine in man. No data are available concerning the preclinical or clinical dependence potential of the drug. There are a few reports of abuse from Chile and Mexico and the drug is controlled in several countries. Fenproporex is used therapeutically as an appetite suppressant and is marketed widely. There are a number of reports of illicit trafficking in the drug.
On the basis of the data outlined above, it was the consensus of the Expert Committee that fenproporex met the criteria of article 2, paragraph 4, for control under the Convention on Psychotropic Substances and should be placed in Schedule IV of the Convention.
ECDD Recommendation
Inclusion in Schedule IV of the 1971 Convention on Psychotropic Substances
Link to full TRS
who_trs_729.pdf1.29 MB