Current Scheduling Status
None
Year(s) and type of review / ECDD meetings
Drug Class
Recommendation (from TRS)
ECDD Technical summary
This substance, commonly known as DOB, is a racemic mixture having the pharmacological profile of a mescaline-like hallucinogen in both animals and man, with an affinity for serotoninergic receptors. In the ‘‘spinal dog"’ the effects of the substance resemble those observed with LSD (lysergic acid diethylamide), with which it is cross-tolerant. In rodents it is discriminated as LSD-like. There is considerable evidence of abuse of this substance from several areas of the world. It has no known therapeutic use; and there are numerous reports of illicit trafficking in the substance. On the recommendation of the Director-General of WHO, the United Nations Commission on Narcotic Drugs has already placed this substance under control in Schedule I of the Convention on Psychotropic Substances. The Expert Committee found no new evidence to recommend a change in this situation.
This substance, commonly known as DOB, is a racemic mixture having the pharmacological profile of a mescaline-like hallucinogen in both animals and man, with an affinity for serotoninergic receptors. In the ‘‘spinal dog"’ the effects of the substance resemble those observed with LSD (lysergic acid diethylamide), with which it is cross-tolerant. In rodents it is discriminated as LSD-like. There is considerable evidence of abuse of this substance from several areas of the world. It has no known therapeutic use; and there are numerous reports of illicit trafficking in the substance. On the recommendation of the Director-General of WHO, the United Nations Commission on Narcotic Drugs has already placed this substance under control in Schedule I of the Convention on Psychotropic Substances. The Expert Committee found no new evidence to recommend a change in this situation.
ECDD Recommendation
Inclusion in Schedule I of the 1971 Convention on Psychotropic Substances
Link to full TRS
who_trs_729.pdf1.29 MB